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Year : 2019  |  Volume : 24  |  Issue : 2  |  Page : 107

Ludwig's angina: Pediatric case report and literature review

Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication17-Sep-2019

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
P.O.Box 55302, Baghdad Post Office, Baghdad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmgims.jmgims_52_18

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How to cite this article:
Al-Mendalawi MD. Ludwig's angina: Pediatric case report and literature review. J Mahatma Gandhi Inst Med Sci 2019;24:107

How to cite this URL:
Al-Mendalawi MD. Ludwig's angina: Pediatric case report and literature review. J Mahatma Gandhi Inst Med Sci [serial online] 2019 [cited 2020 Apr 7];24:107. Available from: http://www.jmgims.co.in/text.asp?2019/24/2/107/267013


I refer to the interesting case report by Singh et al.[1] published in the July–December 2018 issue of Journal of Mahatma Gandhi Institute of Medical Sciences. The authors nicely described a case of Ludwig's angina (LA) in a 6--old Indian boy.[1] In the view of the rarity of that serious infection to occur in infancy with its clinical escalation, I assume that the authors ought to consider compromised immune status in the studied infant. Among conditions associated with compromised immunity, human immunodeficiency virus (HIV) infection is of paramount importance. My assumption is based on the following point. It is noteworthy that due to defective immunity, HIV-positive individuals are more susceptible to infection more than those with a healthy immune system. To the best of my knowledge, HIV infection is a significant health hazard in India. Although no recent data are yet present on the exact pediatric HIV seroprevalence, the available data pointed out to the substantial HIV seroprevalence rate of 1.03% among pregnant in India.[2] Regrettably, the HIV status of the mother of the studied infant was not identified. I presume that some sort of vertical HIV transmission ought to be considered in the studied infant. Therefore, arranging for the diagnostic set of blood viral overload and CD4 lymphocyte count measurements was envisaged in the studied infant. If that set was done and it revealed HIV reactivity, the case in question could be truly regarded as the second novel case report of HIV-associated LA in India. The first case was reported in a 30-year-old male Indian patient with previously undiagnosed HIV patient who presented with necrotizing fasciitis of the right upper chest wall and LA concurrently.[3]

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Singh AP, Tanger R, Mathur V, Gupta AK. Ludwig's angina: Pediatric case report and literature review. J Mahatma Gandhi Inst Med Sci 2018;23:89-91.  Back to cited text no. 1
  [Full text]  
Sibia P, Mohi MK, Kumar A. Seroprevalence of human immunodeficiency virus among antenatal women in one of the institute of Northern India. J Clin Diagn Res 2016;10:QC08-9.  Back to cited text no. 2
Keerthi R, Nayak T. Soft tissue infection of the head and neck in HIV – A vexing diagnostic conundrum. SRM J Res Dent Sci 2016;7:83-90.  Back to cited text no. 3
  [Full text]  


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