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 Table of Contents  
LETTER TO THE EDITOR
Year : 2018  |  Volume : 23  |  Issue : 2  |  Page : 104

Retroperitoneal paraganglioma: A case report with review of literature


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication11-Oct-2018

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, P.O.Box 55302, Baghdad Post Office, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jmgims.jmgims_26_18

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How to cite this article:
Al-Mendalawi MD. Retroperitoneal paraganglioma: A case report with review of literature. J Mahatma Gandhi Inst Med Sci 2018;23:104

How to cite this URL:
Al-Mendalawi MD. Retroperitoneal paraganglioma: A case report with review of literature. J Mahatma Gandhi Inst Med Sci [serial online] 2018 [cited 2018 Dec 18];23:104. Available from: http://www.jmgims.co.in/text.asp?2018/23/2/104/243126



Sir,

I read with interest the case report by Hungund et al. on the retroperitoneal paraganglioma (RP) in an Indian patient published in the latest issue of J Mahatma Gandhi Inst Med Sci.[1] The authors nicely described the clinical picture, radiological features, histopathologic findings, and the treatment protocol in the studied patient. I presume that the rare occurrence of paraganglioma at an unusual site ought to trigger the authors to take into consideration underlying jeopardized immune status in the studied patient. Among jeopardized immune states, infection with human immunodeficiency virus (HIV) is of great importance. My presumption is based on the following point. It is explicit that HIV-positive individuals are more susceptible to various types of neoplasms as compared to immunocompetent individuals. The increased susceptibility has been attributed to many factors, including immunosuppression, coinfection with oncogenic viruses, and life prolongation secondary to the use of antiretroviral therapy.[2] Among neoplasms, paraganglioma has been reported among HIV-positive patients.[3] To my knowledge, HIV infection is an important health threat in India. The available data pointed out to 0.26% HIV seroprevalence compared with a global average of 0.2%.[4] I presume that the authors ought to consider underlying HIV infection in the studied patient. Hence, contemplating the diagnostic set of blood CD4 lymphocyte count and viral overload estimations was envisaged. If that diagnostic set was achieved and it revealed HIV infection, the case in question could be truly considered a novel case report. This is because HIV-associated RP has never been reported in the world literature so far.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Hungund BR, Pattanshetti VM, Pilli GS, Kangle R, Chavan RY. Retroperitoneal paraganglioma: A case report with review of literature. J Mahatma Gandhi Inst Med Sci 2018;23:37-9.  Back to cited text no. 1
  [Full text]  
2.
Valencia Ortega ME. Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases? Rev Clin Esp 2018;218:149-55.  Back to cited text no. 2
    
3.
Fasunla AJ, Ibekwe TS, Afolabi OA, Onakoya PA, Oluwasola OA, Ogun OG, et al. Sinonasal paraganglioma: A case report. Oral Maxillofac Surg 2008;12:93-6.  Back to cited text no. 3
    
4.
Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4.  Back to cited text no. 4
    




 

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